The ultra high risk for psychosis concept - current status and future direction

Presentation First Author: 
Alison Yung

Ultra High Risk (UHR) criteria have been developed over the last 18 years to describe a group putatively in the prodromal stage of a first episode of psychosis. Early research indicated that this group did indeed have a high risk of developing psychotic disorder, mostly schizophrenia. The discovery that it was possible to identify the prodromal phase of psychotic illnesses has had several consequences. Specialised services for this group have developed worldwide and various interventions, ranging from antipsychotic medication to psychological therapies and omga-3 fatty acids, have been trialed. Several strands of research into the aetiopathology of schizophrenia, including generic, neurobiological and neurophysiological research have been conducted. It has also led to a proposal to include a diagnosis of Attenuated Psychosis Syndrome (APS) in the DSM system. So what have we learned from the UHR idea over the last 18 years? This presentation will describe the development of the idea, findings from long term follow up studies, including psychotic and non-psychotic outcomes, and possible future directions.

Conference Name: 
Presentation Date: 
November, 2013
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